Physiologically relevant model systems, can help us better understand cancer biology,  investigate disease mechanisms, and evaluate how  different tumors respond to therapeutic interventions. 

Sushmitha Sankarasubramanian, our next pathbreaker, develops three dimensional (3D) patient-derived organoid models from different cancer types that closely mimic how cancers behave inside the human  body. 

Sushmitha talks to Shyam Krishnamurthy from The Interview Portal about her doctoral research through the PRECODE Consortium  (PancREatic Cancer OrganoiDs rEsearch), a  European Union-funded Marie Skłodowska-Curie  Doctoral Network focused on advancing pancreatic cancer research. 

For students, never take your early years lightly. The effort you invest  in yourself today: whether in your studies, skills, or  character, will become the foundation of the life you  build tomorrow.

Sushmitha, Your background?  

I grew up in a small town called Karur in Tamil Nadu. I  was born into a simple average family. My father is a  businessman, and my mother is a homemaker.  

For some people, childhood is all about fairy tales,  bedtime stories, and picture-perfect memories. My  childhood was a little different. It was filled with its share  of challenges, family problems, disagreements, and  chaos. Yet, through every storm, my parents never  stopped believing in the importance of education and  never gave up on the upbringing of my brother and me.  

One of the greatest influences in my life has been my  elder brother. He is more intelligent, creative and  confident than me. In many ways, he was the compass  that guided my early career choices, and I often found  myself following the path he paved.  

Friendship has always been a special part of my school  life. I was fortunate to have friends who stayed by my  side through the years and eventually became lifelong  companions. While many children spent their time on  sports fields, I discovered joy in studded toys, crafts,  origami and mostly playing in-door games with friends.  I loved making handmade crafts, especially gifts for my  loved ones on their special occasions. And that stayed  with me all along. I still believe that the most meaningful  gifts are the ones created with time, effort, and love.  Some of the warmest memories of my childhood are the  days spent with my brother and our neighbour kid,  Abdul Waahidh, who is more like a younger brother to  me. The time spent with them playing, laughing, fighting and teasing one another are my favourite part of the  childhood. Years have passed, but those moments  remain as one of the fondest memories of my life. 

Among all the subjects I studied in school, Zoology  fascinated me the most. I dreamed of becoming a  doctor and dedicated many of my aspirations to that  goal. However, dreams do not become reality through  passion alone. Looking back, I realize that I did not take  my studies as seriously as I should have during that  phase of my life. Due to my own lack of focus and  maturity at that age, I was unable to secure a medical  seat.  

That disappointment became one of the first major  turning points in my life. When one door closed, I was  unsure which door to open next. I briefly joined  Architecture, but during that time I experienced the loss  of my best friend, a loss that deeply affected me and  changed the course of my life. I eventually discontinued  the course and enrolled in Biotechnology at  Vivekanandha College of Engineering, Namakkal. 

What did you do for graduation?  

I did my B.Tech in Biotechnology at India, Masters in  Molecular Biology from Umeå University at Sweden after which I did a PhD in Human Biology from FAU  Erlangen-Nürnberg at Germany 

Bachelor´s in Biotechnology was not my choice. It was  simply the opportunity available to me at that moment.  But life has a remarkable way of leading us to places  we never planned to go. Sometimes, our greatest opportunities are hidden behind our biggest disappointments.  

My journey taught me an important lesson: success  is not always about following the path you imagined; sometimes it is about making the most  of the path that finds you.  

When I joined Biotechnology at Vivekanandha College  of Engineering, I carried only one thought in my mind:  even though this was not the path I had dreamed of, I  could not afford to let down the people who still believed  in me.  

My family had invested not only their money but also  their hopes in my future. My father’s business went  through many ups and downs, and finances were often  uncertain. My mother, despite facing her own  challenges after a serious accident and living with its  consequences, never stopped putting her children first.  To support my education, my brother moved to Dubai,  even though his heart never wanted to leave India.  Knowing the sacrifices my family was making became  my greatest source of motivation.  

That single thought pushed me to work harder than ever  before. By the end of my undergraduate studies, I was  honoured with the “Best Outstanding Student” award.  What began as a course I never chose , eventually  became a journey that transformed my life.  

What were some of the key influences that led you to a career in cancer research?

Among all the subjects I studied during Biotechnology,  Cancer Biology fascinated me the most. The more I  learned about it, the more curious I became. It was one subject that never bored me.  

I have always believed in one simple principle:  whatever you choose to do, give it your 100% 

I wasn’t chasing opportunities; I was simply focused on  giving my best in every course, project, and  assignment. Looking back, that mindset opened doors  I never expected. It made me earn the opportunity to  complete my thesis at the prestigious Indian Institute of  Science (IISc), Bengaluru, in the Department of  Molecular Biology.  

That experience became one of the most important  turning points in my scientific journey.  

My time at IISc was my first real exposure to scientific  research. For the first time, I experienced what it meant  to work in a world-class research laboratory. I still  remember being taught how to handle laboratory mice.  I was nervous, uncomfortable, and honestly terrified.  That experience helped me discover something  important about myself. I realized that in-vivo research  was not for me. Hence, I was drawn toward in-vitro  research and cellular biology.  

During my time there, I had the privilege of working  under the guidance of Dr. Mohsan Sarikhani, a PhD  researcher who became one of my earliest scientific  role models. What inspired me most was not just his  knowledge, but his passion. He approached science  with genuine excitement and curiosity. To him, research  was not merely a profession, it was something he truly  loved. Working alongside him, conducting experiments,  and uncovering the fascinating complexities of biology showed me what it meant to be a scientist.  

After completing my undergraduate studies, my brother  encouraged me to pursue higher education abroad. He  helped me through every step of the application  process, and I was fortunate to secure admission to  Umeå University in Sweden for a master’s degree in  molecular biology based on my academic performance  alone, with a CGPA above 9, without having to take  exams such as the GRE or IELTS. This was another  major turning point in my life.  

Did you face challenges when you moved to  Sweden? How did you address them?  

I was a person deeply attached to my family. I would  become homesick very easily. Even during my school  years in India, when I stayed in hostels in nearby cities,  I often struggled with being away from home. Moving  alone to Sweden, a country thousand of kilometre’s away with winters reaching temperatures below -30°C,  felt like stepping into an entirely different world.  

I still remember crying throughout much of my 14-hour  journey to Sweden. After landing, I called my family  and begged them to book a return ticket. Many relatives even told my family that sending me to  Sweden was a waste of money because I would never  be able to survive there.  

When I called my brother again from Sweden,  overwhelmed and in tears, he simply said, “If you feel  you cannot stay, come back. I wanted you to  experience the opportunity, not suffer.” “Battles are won in the heart, not in the field” His words stayed with me.  

Once again, I thought about the sacrifices my parents  and brother had made for me. The financial aid for this  dream was given not from an overflow from my dad, but  often amidst his own profound struggles and  challenges. Yet, he bore that pressure so I wouldn’t  have to. My mother, although the thought of me moving  thousands of kilometres away from home worried her deeply, never stood in the way of my dreams. I knew I owed it to them and to myself to give it my best effort  before giving up. Slowly, I adapted to a new culture, a  new education system, and a completely different life.  

I must also express my heartfelt gratitude to my cousin  brother, Vijay Anna, who offered his hands to support  my master´s education during a time when my family’s  finances were strained. His generosity eased a  significant burden on my family. Without his support, completing my master’s degree abroad might have  remained only a dream. His kindness and timely help is something I will always remember and be grateful for. 

Living abroad taught me lessons far beyond  academics. For the first time, I had to manage  everything on my own. I had to learn everything by  myself like opening a bank account, finding a place to  live, cooking every meal, managing finances, and  handling every problem without having any help. I  remember seeing the Northern Lights, something that  appears on many people’s bucket lists. Yet instead of  feeling joy, I felt a strange emptiness because I didn’t  have my loved ones there to share that moment with. 

The journey was not easy. I went from being someone  who felt nervous even traveling alone to the next street,  to moving across continents and building a life from  scratch in Sweden. Along the way, I faced setbacks,  trusted the wrong people, got scammed, lost money,  and experienced the challenges that often come with  living alone in a new country. There were days when I  questioned why I had come. Days when I missed home  so much that even a simple phone call could bring me  to tears. While everyone saw the exciting photographs  and the opportunities abroad, very few saw the  struggles behind them: the loneliness, the self-doubt,  and the silent battles that came with starting over in a  foreign country.  

I am especially grateful for the friends I met in Sweden.  They became much more than friends. During some of  my hardest moments, they were the people who  listened, supported me, and reminded me that I was not  alone. I will always be thankful for the role they played  in my journey.  

The academic transition was also challenging. The  coursework was rigorous, and at times I doubted  whether I could keep up. But perseverance became my  greatest strength. By the end of my master’s program, I  had passed every course with distinction, secured two  research stipends which helped me to fund myself a bit  during my master´s, and successfully completed two  independent research projects.  

My fascination with Cancer Biology grew even stronger  during my master´s. I actively searched for laboratories  working in cancer research and eventually joined the laboratory of Dr. Daniel Öhlund, whose team focuses  on pancreatic cancer research using human cancer patient-derived organoids. During my time there, I  completed two independent research projects  supported by research stipends from the  Cancerforskningsfonden i Norrland, which helped me in supporting myself financially during my studies. I worked  closely with Dr. James Mason, who was a postdoctoral  researcher at the time and played a pivotal role in  teaching me the fundamentals of organoid research  and experimental science. He was not only an  exceptional scientist but also an outstanding mentor  who helped nurture my curiosity, scientific thinking, and  confidence as a young researcher. Those experiences  further strengthened my passion for cancer research. 

At IISc, most of my work involved bacteria and animal  models. Yet I often found myself wondering what it  would be like to work directly with human samples. I  dreamed of conducting research that could bring us  closer to understanding diseases affecting real patients. At that time, I had no idea that this dream was  about to become a reality. 

Working with human patient-derived organoids was  one of the most fascinating experiences of my  scientific journey.  

Can you explain what are Organoids and what are  the advantages? 

Patient-derived organoids are like “mini tumours grown  in a dish in a 3D environment.” Scientists take a small  sample of a cancer patient’s tumour and grow it in the laboratory in a 3D environment, under conditions that  closely resemble the human body. These mini tumours behave much like the real tumour, allowing us to study cancer from different patients. By understanding how these organoids respond to different medicines, we can  develop better and more personalized treatments for  cancer patients in the future. It was the first time I felt I  was working with a model system that had a direct  connection to real patients and their lives.  

During this time, I also discovered something important  about myself: I genuinely love learning new  technologies. Whenever someone in the laboratory was  working on a technique I did not know, I would walk  over, observe, ask questions, and sometimes even  spend hours learning about it. I was fascinated by the  idea that every new technology could unlock answers  to questions that were previously impossible to solve.  

This experience taught me that when science and  technology work together, they have the power to  transform healthcare. Technologies such as 3D cell  cultures, advanced imaging, and modern molecular  tools are much more than laboratory techniques. They  help scientists understand diseases better, develop  new treatments faster, and ultimately improve the lives  of patients. In many ways, they act as a bridge between  discoveries made in the laboratory and real benefits  delivered to people in hospitals.  

How did you get your first break?  

As much as I enjoyed research, I gradually realized that  a traditional academic career was not the path I wanted to follow. I have immense respect for scientists who  dedicate years, and sometimes even decades, to  uncovering the mysteries of biology and advancing our  understanding of life at its most fundamental level.  However, I found myself increasingly drawn to a  different question:  

How can we turn scientific discoveries into  something that helps real patients sooner?  

I wanted to work closer to clinical and translational  research, where discoveries made in the laboratory  could be transformed into therapies, diagnostics, and  solutions that directly impact patients’ lives.  

At the same time, I learned something important about  myself. I love doing science, but I also value having a  balanced and fulfilling life outside of work. I knew that I  wanted a career where I could continue learning,  contribute to meaningful innovations, be recognized for  my work, and build financial stability, while still  maintaining a healthy work-life balance.  

For me, the pharmaceutical and biotechnology industry  seemed to offer the best of both worlds, the opportunity  to do exciting science while seeing its impact more  quickly and building a sustainable long-term career. 

With that vision in mind, I began searching for an  industrial master’s thesis opportunity. Almost everyone  around me told me it would be nearly impossible to  secure one, especially at a leading pharmaceutical  company. But throughout my life, I have always  believed in trying, even when the chances seem incredibly small.  

My philosophy has always been simple:  

If there is even one chance in a billion, I would  rather try and fail than wonder forever what might have happened if I had tried.  

So, I created my CV and reached out to professors  and scientists at AstraZeneca in Sweden. One email  became ten. Ten became fifty. I kept going.  

Eventually, I secured a master’s thesis position in  AstraZeneca’s Respiratory Research Department  under the supervision of Dr. Henric Ohlsson. There, I  worked on projects investigating the disease biology of  asthma and chronic obstructive pulmonary disease (COPD). 

Beyond the scientific experience, this was my first  exposure to research in a global pharmaceutical  company. Dr. Henric Ohlsson played a significant role  in helping me understand how science is conducted in  an industrial setting, where scientific innovation,  teamwork, and patient impact go hand in hand.  Through this experience, I gained my first insights into  corporate culture, professional values, cross-functional  collaboration, and the process of translating scientific  discoveries into therapies that can benefit patients.  The experience further strengthened my desire to  pursue a career in the biotechnology and  pharmaceutical industry. 

After completing my thesis, I was offered the  opportunity to continue working as a full time  Research Scientist in AstraZeneca’s Pharmacology Department. There, I worked with mass spectrometry based approaches aimed at improving the solubility and permeability of therapeutic compounds.  

How did you plan the steps to get into the career  you wanted?  

At that stage of my life, a PhD was not even part of my  plan. My dream was to build a career in the  pharmaceutical industry and continue growing in that  environment. However, life once again had different  plans for me. Due to a mistake on my part, I was unable  to renew my visa and residence permits on time, which  forced me to return to India. At the time, it felt like a  major setback. I was disappointed in myself and  frustrated that a simple oversight could change the  course of my plans.  

Coming back home was emotionally complex.  

Part of me felt relieved because the loneliness of living  abroad had been difficult. Yet another part of me  struggled with leaving behind the life I had built in  Sweden: the snowy winters I had learned to love, the  friendships I had formed, and the feeling that I had not  yet fully achieved what I had hoped for after investing  so much into my education.  

But by then, I had learned an important lesson:  

Life does not always reward us with the outcome  we want, but it always rewards us with experience that prepares us for the next opportunity.  

After returning to India, I once again focused on moving  forward. I joined Enveda Biosciences, a US-based pharmaceutical company, as an Associate Scientist.  The company was focused on developing novel cancer  therapeutics inspired by bioactive compounds derived  from medicinal plants. Although I spent only a short time  there, the experiences gained there are still a valuable  part of my journey. I had the privilege of meeting and  working under Dr. Viswa Colluru, a scientist and leader  whom I still deeply admire, not only for his scientific  expertise but also for the values he lived by: humility,  integrity, kindness, and an unwavering commitment to  excellence. 

One lesson from Dr. Viswa Colluru has stayed with me  throughout my journey: 

“People may forget what you did, but they will never  forget how you made them feel.” 

That quote by him changed the way I view success.  Achievements may be remembered for a while, but who  you are as a person will leave a lasting impact on  others. 

How did you make a transition to a new career?  Tell us about your career path ?  

While working as a scientist in India I began to  understand the realities of the global research landscape. For someone with a master’s degree hoping  to build an international scientific career, obtaining  opportunities abroad could be challenging. Companies  often preferred candidates who were already local and had advanced research training in the same country. At  the same time, I was carrying the responsibility of  educational loans from my studies abroad. 

Slowly, I began considering a path I had never  imagined for myself, a PhD. 

Another factor that influenced my decision was my  time at AstraZeneca. There, I noticed that many of the  scientists in senior scientific and leadership positions held PhD degrees. It made me realize that if I wanted  to grow further in research and take on greater  scientific responsibility, a PhD could open doors that  might otherwise remain closed. 

Ironically, the very degree I had once ruled out  became the door that opened my next opportunity.  

So, I started applying for PhD positions. To my surprise,  despite all the self-doubt I carried, I was selected for  one of the most prestigious doctoral programs  available: a Marie Skłodowska-Curie Fellowship.  

It´s a highly competitive fellowship and one of the  best-funded PhD programs in Europe. The fellowship  offers a higher salary than many standard PhD  positions, which helps researchers to focus on their  research, training, and international collaborations  without as much financial pressure. I obtained my PhD  position through the PRECODE Consortium  (PancREatic Cancer OrganoiDs rEsearch), a  European Union-funded Marie Skłodowska-Curie  Doctoral Network focused on advancing pancreatic cancer research. 

The consortium brought together 15 leading  institutions across seven European countries,  including top universities, research institutes,  hospitals, and biotechnology companies working at the  forefront of pancreatic cancer research. Only 13 PhD  positions were available across the entire network,  and candidates from all over the world competed for  these positions. 

What made the selection process particularly rigorous  was the mobility rule of the fellowship. Applicants  could not simply remain in the same country where they had recently studied or worked. The goal was to  promote international collaboration and ensure that  researchers gained experience in new environments.  As a result, each institution had to conduct a thorough  international recruitment process and select the  strongest candidates. 

My previous experience in pancreatic cancer research and patient-derived organoids during my master’s thesis gave me a strong foundation. I also received an  excellent recommendation from my Master’s  supervisor, Dr. Daniel Öhlund, who was himself a  member of the PRECODE consortium. However,  because of the consortium’s mobility requirements, I  could not continue my PhD in his laboratory. Instead, I  applied for positions in other PRECODE partner  institutions, including opportunities in Spain and  Germany. 

I received offers from both locations. Since my long-term goal was always to build a career in the  pharmaceutical industry, I chose the position in  Germany because it offered an Industrial PhD. Unlike  a traditional PhD, where research is conducted  primarily within a university, my research was carried  out full-time at CellPhenomics, a biotechnology  company that was later acquired by GSK. However,  companies cannot award doctoral degrees. Therefore,  I was simultaneously enrolled as a PhD candidate at  Friedrich-Alexander University (FAU) Erlangen Nürnberg in Germany, solely to submit my thesis and  to obtain the degree. 

I began to wonder whether life had been guiding me  toward something larger than I had imagined.  

Perhaps the universe was telling me not to limit  myself. Yet accepting the PhD position was one of the  most frightening decisions I had ever made.  

For years, I had believed that a PhD was only for  exceptionally brilliant people. I worried whether I was  intelligent enough, whether I could think critically  enough, or whether I had the perseverance required to  complete such a demanding journey.  

And if pursuing a PhD was intimidating, pursuing one  through a highly competitive international fellowship  felt even more overwhelming.  

But every major chapter of my life had begun the  same way, with uncertainty, fear, and a leap of faith.  

So once again, with a heart full of questions, eyes  filled with tears, and a suitcase packed with dreams  and doubts, I boarded a flight to Germany. I did not know what challenges awaited me.  

I only knew one thing: Every time life had pushed me  out of my comfort zone, it had helped me discover a  stronger version of myself. 

Was this PhD research the same as your early wet  lab research based on Organoids? Since you  worked on Pancreatic cancer in your Master’s,  how was the PHD different? 

My PhD was closely connected to my master’s research because both focused on pancreatic cancer  and patient-derived organoids. However, the scientific  questions, clinical relevance, and potential impact  were very different. 

During my master’s projects, I worked on  understanding fundamental aspects of pancreatic  cancer biology utilizing organoid models, particularly  exploring ways to improve early detection of the  disease. This is especially important because  pancreatic cancer is often diagnosed at a very late  stage, when treatment options are limited and patient  outcomes are poor. 

My PhD, on the other hand, had a much stronger  clinical and translational focus. The objective was to  develop a standardised patient-derived organoid assay that enables the generation of miniature tumor  models from an individual patient’s cancer tissue.  These models could then be used for functional drug  screening, allowing us to evaluate multiple therapeutic options and identify the treatment most likely to be  effective for that specific patient.

The broader vision of this work was to support the  implementation of personalized medicine, where  treatment decisions are guided not only by the clinical  guidelines but also by its actual response to therapies  in a patient-specific model system. 

In simple terms, my research aimed to answer a very  important question: 

“How can we find the right treatment for the right  patient at the right time?” 

For me, it would be a dream come true if one day  patient-derived organoid technology becomes a  routine part of cancer care in hospitals worldwide. If  we can use these models to select the most effective  therapy for each patient, we could improve quality of life, avoid unnecessary treatments, and ultimately  increase the survival of cancer patients. 

Tell us about your PhD journey  

When I accepted the Marie Skłodowska-Curie  Fellowship and moved to Germany, I did not realize  that this journey would challenge me far beyond  science and research.  

A PhD is often described as a degree, but for me it  was a test of everything I was.  

It demanded everything from me, not just long working  hours and late nights in the laboratory, but also  tolerance, resilience, patience, and the courage to keep  going when I doubted myself. There were days filled  with excitement and discovery, but there were also days filled with self-doubt, imposter syndrome, uncertainty,  and the constant pressure of proving myself.  

This phase made me understand that growth is not  always comfortable. Sometimes growth feels like  failure. Sometimes it feels like fear. Sometimes it feels  like taking one step forward after taking two steps back.  

The challenges were not limited to academics alone.  

While navigating the demands of my PhD, I was also  carrying personal responsibilities and family difficulties  back home in India. Many of those experiences were  deeply personal and difficult to talk about, but they  taught me one of the most important lessons of my life:  strength is not about having no struggles; it is about  continuing despite them.  

At the same time, my PhD years brought experiences  that shaped me in unexpected ways. It was during  this period that I experienced some of the happiest  moments of my life. I formed meaningful relationships  learned to open my heart, embraced vulnerability, and  discovered parts of myself I had never known before. It was also a period that taught me some of life’s  deepest lessons about attachment, loss, and  resilience. Not every meaningful chapter is meant to  last, but some leave behind lessons that stay with us  forever. 

Looking back, I can honestly say that no other period of  my life has brought me so much joy and so much pain  at the same time. I have never laughed as much as I did  during my PhD. And I have never cried as much either.  

The journey gave me memories that I will cherish forever and lessons that I will carry for the rest of my  life.  

But through every challenge, one thought remained  constant. I wanted to finish my PhD, no matter what.  Not only for myself, but for every person who had  believed in me when I could not believe in myself. And  even for those who are no longer part of my life, but  whose support, love, encouragement, and sacrifices  helped shape the person I became.  

There were many moments when giving up would  have been easier.  

But every time I felt like quitting, I reminded myself that  this journey is not just about me. The degree may have  my name on it, but the journey belongs to everyone who  helped me reach the finish line.  

While the path was mine to walk, it was never mine  to walk alone.  

I am deeply grateful to all my teachers from school to  college/university who nurtured my curiosity,  encouraged me during difficult times, and helped  shape my future. It would be difficult to name everyone  who guided, supported, and believed in me along the  way, but each of them played a role in helping me  become the person I am today. I am also thankful to  my relatives and family members, who never stopped  encouraging me and were always proud of my  achievements, both big and small 

I am especially thankful to mentors like Dr. Daniel  Öhlund during my Master’s and Dr. Christian  Regenbrecht & Dr. Lena Wedeken during my PhD. 

Without their guidance, I would not be where I am  today. The lessons they gave me are among the most  valuable things I carry forward scientifically and  personally, and I hope to pass them on to others  throughout my own journey. Dr. Lena Wedeken who  was my PhD supervisor, has been an inspiring  exemplar of women’s leadership, demonstrating how  to be successful, ethical, and compassionate at the  same time. She shaped my scientific character I will  always be grateful for the lessons and values I learned  from her. 

Where do you work now?  

After completing my PhD, I worked briefly as an  Associate Scientist at GSK following the acquisition of  the company where I was pursuing my industrial PhD.  Soon after, I secured a Scientist position at Indivumed  in Hamburg, Germany. It was a highly competitive  process involving five rounds of interviews against  candidates including researchers with postdoctoral  experience.  

Looking back, it was a proud moment for me not  because I was the smartest candidate among the ones  competing, but because I achieved it during one of the  darkest periods I had ever faced. At that time, my  physical health, mental health, and personal life were  all being tested in ways that are difficult to put into  words. There were days when simply getting out of bed  felt like climbing a mountain. There were moments  when I questioned myself, my future, and whether I had  the strength to keep going. Sometimes, the strongest  version of yourself is born during the hardest chapter of your life.  

I am grateful to my family, especially my brother and  sister-in-law, who were my pillars of strength during  some of the most difficult moments of my life. My sister in-law, who is a sister not by blood but by heart, was my  emotional anchor through it all. She constantly  encouraged me to push beyond my fears and  limitations, even when I did not want to do it for myself.  She is someone I deeply admire, respect and learn  from. 

What problems do you solve?  

My current work focuses on developing three dimensional (3D) patient-derived organoid models  from different cancer types. These miniature tumor  models are generated from patient tumor samples and  closely mimic how cancers behave inside the human  body. 

By using these physiologically relevant model systems, we can better understand cancer biology,  investigate disease mechanisms, and evaluate how  different tumors respond to therapeutic interventions.  Ultimately, these models serve as a powerful platform  for the discovery and development of new cancer  therapeutics.  

What skills are needed for this job? How did you  acquire them?  

Many people believe that scientists are born  exceptionally intelligent or naturally gifted. My  experience has taught me something different.  

The most important skill is not intelligence or creativity, it’s curiosity. A good scientist is someone  who never stops asking questions and never stops  learning.  

Of course, skills such as critical thinking, problem solving, and creativity are important. But none of these  are qualities that you must be born with. They can all  be learned and improved with practice. 

I acquired these skills step by step: through my studies,  research projects, failures, mistakes, and by constantly  challenging myself to learn something new. Every stage  of my journey, from a small town in Tamil Nadu to  research laboratories in Europe, taught me valuable  lessons.  

What’s a typical day like?  

One of the things I love most about my job is that no  two days are exactly the same.  

A typical day may involve designing scientific  experiments, working in the laboratory, analyzing data,  discussing results with colleagues, solving unexpected  problems, and presenting findings to both scientific and  non-scientific audiences.  

Some days I am wearing a lab coat and conducting  experiments. Other days I am sitting with teams from  different scientific backgrounds, discussing ideas and  planning future research.  

Every day brings a new challenge and a new  opportunity to learn.  

What is it you love about this job? 

What I love most is that learning never stops. Science  constantly evolves, and so do the people who work in  it. Every new experiment teaches me something I did  not know the day before. Every challenge pushes me to  think differently and grow.  

I believe that this is how life should be: not only in our  careers but also as individuals. We should never stop  learning, improving, and becoming better versions of  ourselves. That is why I love being a scientist.  

How does your work benefit society? 

In simple terms, my job is to help answer one  important question:  

“How can we find the right treatment for the right  patient at the right time?”  

Every day, I work with a team of scientists to better  understand cancer and discover more effective therapies. Each experiment may seem small, but every  result adds another piece to a much larger puzzle.  

Since you have a very wide range of work, any  specific memorable project? 

Rather than one memorable project, I would say that  my scientific journey has been filled with many  memorable moments.  

Some of my most exciting moments came when I saw  science come alive right in front of my eyes. I still  remember the feeling of amazement when lung  organoids developed tiny moving cilia, when colon  organoids formed crypt-like structures, and when  pancreatic organoids organized themselves into duct-like networks. In those moments, I truly understood how  remarkable science is and how far human knowledge  can advance when curiosity meets hard work.  

A scientist may spend weeks, months, or sometimes  even years designing experiments, solving problems,  and testing ideas. Most experiments do not work the  way we expect; many fail completely, forcing us to go  back, rethink our assumptions, and develop new hypotheses. 

That is the reality of science. Which is why the rare  moments when an experiment finally works and the  results match what you predicted feel almost magical.  Those moments bring an excitement that is difficult to  describe. They remind you that every failure, every late  night, and every challenge was worth it. 

It´s like solving a puzzle that nature had hidden for us,  and for a brief moment, discovering a small piece of the  answer. 

Your advice to students based on your  experience?  

Never take your early years lightly. The effort you invest  in yourself today: whether in your studies, skills, or  character, will become the foundation of the life you  build tomorrow. One day, your future self will thank you  for every hour you spent learning instead of giving up. 

Always give your best in whatever you do. You may not  always get the result you want, but you will never regret  giving your 100%.  

At the same time, do not get so busy chasing achievements that you forget to enjoy your childhood.  Learn, dream, work hard, but also laugh, play, create  memories, and build meaningful friendships. Years  later, your grades may fade from memory, but the  people with whom you shared laughter, experiences,  and memories will remain among your greatest  treasures. 

And when life closes a door, do not lose hope.  Sometimes it is not closing a door to punish you, it is  guiding you toward a door you never knew existed.  

Most importantly, let gratitude become your fuel  when motivation runs out.